Politico's Kasie Hunt reports

Rep. Mike Pence is expected to announce late Thursday whether he is running for president, POLITICO has learned. The announcement will appear first in the Indianapolis Star, an aide said.

I think it's now or never for a Pence presidential run, but that doesn't mean it's an easy decision. 

Update: the Indy Star reports that Pence will make his announcement in an interview with the paper after 7:00 p.m.