Sen. Jeff Flake, R-Ariz., has said he will support Brett Kavanaugh when the Senate votes - a major boost for the embattled Supreme Court nominee.

When asked Friday if he plans to go "Yes" in the final vote, Flake said, "Unless something big changes." And when asked if Kavanaugh will get confirmed, Flake said, "I would think so."

Susan Collins, R-Maine, remains undecided and will declare her verdict on the Senate floor Friday afternoon. Wavering Democrat Joe Manchin, D-W.Va., has still not made his intentions known.

But the third holdout Republican, Lisa Murkowski, R-Alaska, has broken GOP ranks to say she will be a No on Kavanaugh.

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Kavanaugh's nomination has been in doubt after Flake and two other Republican senators backed a one-week delay to give the FBI more time to examine sexual assault allegations against the nominee.

Both Flake and Sen. Susan Collins, R-Maine, voted to end debate on the nominee, a step toward a final vote, but Murkowski of Alaska, voted to continue discussion.

"Of course. Of course. This is a difficult decision for everybody. It really is. And so, anyway. we did our best," Flake said when asked if it was a hard decision for him. "But anyway, I’m glad we had a better process. We needed a better process."

While Flake was saying he would vote for Kavanaugh, Murkowski told reporters that she was a "No" vote.

“I believe that Brett Kavanaugh is a good man. I believe he is a good man. It just may be, that in my view, he’s not the right man for the court at this time,” said Murkowski.

Murkowski said she would be returning to her office to write a more “fulsome” floor statement about her decision. “But this has truly been the most difficult evaluation of, decision, that I’ve ever had to make,” she said.

Now that Flake is a "Yes", Republicans won't need Murkowski if Collins supports Kavanaugh Collins has said she would reveal her intentions in the final vote in a 3 p.m. Senate floor speech.

Sen. Joe Manchin, D-W.Va., also supported Kavanaugh in Friday's procedural vote, a sign that he too might be a "Yes" in the final vote.