April Jacobowitz's family knew something was wrong when she didn't contact one of her children on a birthday.

The Germantown woman was estranged from her family, according to data from the National Missing and Unidentified Persons System, or NamUs, but kept in touch with her two young children, who were living with her parents. On May 13, 2003, she missed one of her children's birthdays, and her family reported her missing. NamUs data did not specify why Jacobowitz was estranged from her family or why her children were living with her parents.

There had been no activity in Jacobowitz's bank account since February 2003, according to NamUs, and though she'd apparently left the Germantown area in late 2002, she didn't have access to a car.

According to data from the North American Missing Persons Network, Jacobowitz is on medication for mental disorders. She didn't have her medicine with her when she disappeared, however.

Jacobowitz was 33 when she disappeared and would be 42 years old today. She weighed 100 to 110 pounds, stood 5 feet 3 inches tall, and had brown hair and green eyes. She had been living on the 12400 block of Great Park Circle but likely left that area around November or December 2002, according to NamUs.

Anyone with information on the case can call the Montgomery County police's 5th District at 301-840-2347 and reference case number G03108668.