Iran's top leader, Ayatollah Ali Khamenei, in a major national address Saturday said the historic nuclear deal would do nothing to alter its stance toward the "arrogant" United States.

In a speech televised throughout Iran and the Middle East, Khamenei all but assured that some of the sanctions relief the deal provides will continue to flow to Hezbollah and other terrorist organizations as well as Palestinian groups and the Syrian government.

"Our policy toward the arrogant U.S. government won't change at all," he said in a speech to a large crowd in Tehran marking the end of the Muslim holy fasting month of Ramadan, according to the Associated Press.

His remarks appeared to be aimed at undermining comments from President Hassan Rouhani who earlier this week after the deal was struck that the deal could "step-by-step remove bricks from the wall of mistrust" between the Tehran and Washington as long as both sides complied with the details of the agreement.

"U.S. policies in the region are 180 degrees in contrast to Iran's policies," Khamenei reportedly said. "Whether this text [of the nuclear deal] is approved or disproved, we won't give up supporting our friends in the region. The oppressed Palestinian nation, Yemen, Syria, Iraq, Bahrain, the honest mujahedeen of resistance in Lebanon and Palestine will enjoy our constant support."

President Obama and U.S. officials basically mirrored the comments from their own viewpoint this week, arguing that the deal would not turn our longtime foe into a friend.

"… Even with this deal, we will continue to have profound differences with Iran: its support of terrorism, its use of proxies to destabilize parts of the Middle East," Obama said during a press conference.

The president also noted that the U.S. would maintain sanctions on Iran for terrorism, its ballistic missile program, its human rights violations, as well "our unprecedented security cooperation with Israel" and partnerships with the Gulf states.

Still, Obama said he believed that after the deal and unprecedented two years of negotiations between the two countries, Iran might "move in a different direction."

"The path of violence and rigid ideology, a foreign policy based on threats to attack your neighbors or eradicate Israel – that's a dead end," he said in a Tuesday statement announcing the deal.

"A different path, one of tolerance, and peaceful resolution of conflict, leads to more integration into the global economy, more engagement with the international community, and the ability of the Iranian people to prosper and thrive."