Donald Trump's Tuesday night victory speech demonstrated why he would be a tricky general election opponent for Hillary Clinton while at the same time reinforcing all the reasons so many Republicans believe he cannot win.

Let's start with the positives. Trump can hit Clinton from the right, left and center. He talked about wage stagnation, job losses, bad trade deals and Wall Street greed. Trump can run against Clinton's corporate ties without sounding like a socialist, hit her for NAFTA and her vote for the Iraq war.

That's not a stereotypical Republican platform. But it is a potentially popular one, especially in a time of economic anxiety. It is one that can appeal to some disaffected Bernie Sanders voters, many more rank-and-file Republicans than the party establishment would prefer to believe, independents and blue-collar Democrats.

It all dovetails pretty nicely with what some analysts describe as the "new American center."

But the takeaway from Trump's remarks will almost certainly be his contention that if Clinton was a man, she wouldn't even win 5 percent of the vote. "The only thing she has going is the woman's card," he said.

Clinton is by her own admission not the most skillful politician. Yet saying that all Clinton has is her gender after feuds with Megyn Kelly and Rosie O'Donnell, after retweeting an unflattering image of Heidi Cruz, after commenting on Carly Fiorina's appearance, after polls show more than 60 percent of Americans don't think Trump respects women... maybe not so smart.

As it happens, Clinton preemptively brought up Trump's reference to the "woman's card" in her own victory speech. She also made an appeal to "thoughtful Republicans," suggesting she knows that there are suburban, college-educated Republicans who will be repulsed by Trump's style if not his substance.

Trump is an interesting candidate who can shake up the electorate in ways that will be difficult for Clinton to predict. But some of that shaking up won't be to the liking of traditional parts of the Republican base while he has already made it more difficult to appeal to some of the minority voters who could be receptive to his message about globalization's downside.

Trump could beat the most powerful factions in the Republican Party en route to the nomination in Cleveland. But he can't fight everyone heading into November and hope to avoid disaster.