The top executive of the company that raised the price of its EpiPen 400 percent may come to Capitol Hill to face questions from lawmakers about the sudden increase.

The twist is the CEO is very familiar to one lawmaker. Mylan CEO Heather Bresch is the daughter of West Virginia Democratic Sen. Joe Manchin, Bloomberg News reported.

The EpiPen's recent spike to about $500 a dose for the life-saving allergy shot is the latest increase by the industry to spark outrage from lawmakers. Manchin's colleague, Sen. Chuck Grassley, R-Iowa, wrote to Mylan asking for answers behind the price boost.

Sen. Richard Blumenthal, D-Conn., wants the Federal Trade Commission to investigate whether Mylan violated antitrust laws, Bloomberg said.

Rep. Grace Meng, D-N.Y., called for a House hearing on Tuesday on the issue as well.

Hillary Clinton is the latest politician to express outrage over the price hike, which is the most recent in a line of huge increases by drug makers.

Clinton said in a tweet that "EpiPens can be the difference between life and death. There's no justification for these price hikes."

So far Manchin has been mum about the issue, according to Bloomberg.

Manchin has been a major advocate for fighting opioid abuse, which has ravaged West Virginia. He has criticized the Food and Drug Administration for continuing to approve new opioid products, and objected to the confirmation of the agency's new commissioner Robert Califf due to concerns about the agency's response to the opioid crisis.

The price increase for EpiPens also is prompting outrage because a 2013 bipartisan law requires schools to stock the drug to prepare for any health emergencies.